Monday, 20 September 2021– 2nd Symposium EVIta
Welcoming Day
15.00-17.00
Welcome
Registration and Welcome coffee
15.00-17.00
16.00-17.00
Pre-meeting
Showcase of International collaborative projects and networks on Extracellular Vesicles.
Chairs: Marcella Chiari, Annalisa Radeghieri
Caterina Nardella, Laboratory of Computational and Functional Oncology Department of Cellular, Computational and Integrative Biology – CIBIO, Trento University, AIRC Accelerator Award, project acronym PRIME
17.15-17.30
Opening Ceremony
17.15-17.30
17.30 - 19.00
Invited Lecture Session
Chairs: Benedetta Bussolati, Annalisa Radeghieri
17.30-18.00
Invited Lecture 1
17.30-18.00
18.00-18.30
Invited Lecture 2
18.30- 19.00
Invited Lecture 3
18.30- 19.00
19.00-19.30
Round Table
New landscapes in EV research and applications.
Chairs: Benedetta Bussolati- Annalisa Radeghieri and project coordinators.
20.15
Dinner
20.15
Thusday, 21 September 2021– 2nd Symposium EVIta
1st Day
9.00 - 9.30
Invited Lecture
Chairs: Stefania Bruno, Lorenza Lazzari
Bernd Giebel - Mesenchymal Stem Cell-derived Extracellular Vesicles: a Potential New Tool in Regenerative Medicine.
9.00 - 9.30
9.30-10.45
Oral presentations - EV isolation and characterization.
Chairs: Stefania Bruno, Lorenza Lazzari
Dario Brambilla - INDEX: development of an integrated platform to provide EV-based liquid biopsy for lung cancer.
Ramila Mammadova - Identification of viral particles copurifying with tomato-derived nanovesicles by shotgun proteomics.
Giorgia Adamo - Extracellular vesicles from microalgae: anti-oxidant bioactivity and cellular uptake studies.
Andrea Zendrini - Specific antithrombin glycoforms adsorb onto plasma extracellular vesicles.
10.45-11.15
Coffee break
10.45-11.15
11.15-12.45
Oral presentations - EV biomarkers and therapeutics.
Chairs: Marina Cretich, Gabriella Pocsfalvi
Orazio Fortunato - Circulating extracellular vesicles as biomarkers of response for immune-checkpoint inhibitors in advanced NSCLC.
Manuela Basso - Decoding distinctive features of plasma extracellular vesicles in amyotrophic lateral sclerosis.
Ambra Costa - Human amniotic fluid stem cell-extracellular vesicles support cardiomyocyte renewal.
Mario Barilani - Human induced pluripotent stem cells as inexhaustible source of extracellular vesicles for acellular therapy.
Loredana Casalis - Extracellular vesicle-model membranes interaction: a non-total fusion mechanism.
13.00-14.30
Lunch
Restaurant “La veranda”
13.00-14.30
14.30-16.00
Poster Session 1 - Coffee break
16.00-17.00
Sponsor Session
Beckman Coulter - Pure preparations, proven reagents and accurate characterizations – 2021 update on BEC LS solutions supporting Exosomes & Extracellular Vesicles research.
Alfatest - Are we facing Exosomes?
Schaefer South-est Europe - Extracellular Vesicles: Automating your Research for Isolation and Accurate Single Particle Characterization.
Particle Metrix GmbH - Improvements in fluorescent Nanoparticle Tracking Analysis : Reliable characterization of Extracellular Vesicles.
Luminex Corp - High resolution flow cytometric analysis of extracellular vesicles with the Luminex Amnis-Cellstream Instrument.
ONI – Oxford Nanoimaging - Single-molecule imaging of extracellular vesicles below the diffraction limit.
16.00-17.00
17.00-18.15
Oral presentations
Chairs: Cristina Grange, Nunzio Iraci.
Session 1- EVs and COVID-19.
Balbi Carolina - Circulating extracellular vesicles are endowed with enhanced procoagulant activity in SARS-CoV-2 infection.
Roberta Verta - Generation of spike-extracellular vesicles (S-EVs) as a tool to mimic SARS-CoV-2 interaction with host cells.
Session 2- Model systems.
Pamela Santonicola - Caenorhabditis elegans as model system to study EV bioactivity and biodistribution in vivo.
Ferrari Luca - Extracellular vesicles carrying human endogenous retroviruses as modulators of immune response after environmental stimuli: functional studies in the zebrafish model.
20.00
Gala Dinner
Auditorium Sala Pascoli
20.00
Wednesday, 22 September 2021– 2nd Symposium EVIta
2nd Day
8.30-9.30
General assembly EVIta members
8.30-9.30
9.30-11.00
Oral presentations - EVs in pathogenesis of diseases.
Chairs: Marina Camera, Maria Felice Brizzi
Loredana Leggio - Astrocyte-derived extracellular vesicles from specific brain regions rescue apoptosis and preserve mitochondrial function in a cellular model of Parkinson’s disease.
Silvia Picciolini - Evaluation of neural extracellular vesicles release after the inhibition of neutral sphingomyelinase in acute brain injury.
Serena Maggio - Pro-inflammatory activity of extracellular vesicles released by senescent-like muscle cells.
Noemi Torriero - The role of oxygen tension on 3D Neuroblastoma spheroids and their shredded exosomes: could hypoxic exosomes modulate Mesenchymal Stem Cells behavior?
Malvina Koni - nEVs increase tumor metastasis in a 4T1 mouse triple-negative breast cancer (TNBC) model.
12.30-13.00
Final lecture
Chair: Antonella Bongiovanni.
Dolores Di Vizio - Heterogeneity of Extracellular Vesicles in Interferon Pathway Activation
13.00-13.30
Wrap up, awards and closing remarks
13.00-13.30
13.30
Lunch
Restaurant “La veranda”
